Vloom Focus® : Research-Backed Up Lion's Mane, Premium Mushroom Supplement

Cognitive Enhancement, Mood Support, and Gut Health

Vloom-Focus is a unique supplement, fully evidence-based, researched by numerous educational and health institutions, and certified with the highest EU and USA standards of quality. It is formulated with Lion's Mane mushroom (Hericium erinaceus) organic biomass, to preserve all the bio-portofolio of its natural, beneficial compounds. It is a natural nootropic and prebiotic, with a more than 3000 years recorded history of use in Chinese Traditional Medicine (CTM). Unlike other Lion's Mane mushroom products, Vloom-Focus leverages a patented production process that preserves the mushroom's full spectrum of bioactive compounds, ensuring its maximum efficacy and natural mechanisms of actions, including antioxidant and detoxifying enzymes (usually excluded from other extraction production processes), as well as key nootropic, anti-inflammatory, immunomodulatory, and prebiotic activity (1,2). 

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Scientific Evidence Supporting Vloom Focus

A growing body of research supports the benefits of Lion's Mane mushroom for cognitive health, mood support, and gut health. Vloom Focus leverages this scientific foundation and builds on it with its own unique contribution (see Bibliography below). Clinical human observations and laboratory studies specifically made with Vloom Focus have demonstrated its potential in various areas, including its natural support for neurodegenerative conditions and the betterment of their cognitive decline symptoms, cognitive boost in healthy patients, improvement in patient’s sleep, anxiety reduction, mood and gut microbiome balancing effects, in addition to its unique biomass nutritional advantages, anti-age (potent anti-oxidant and detoxifier), and skin regeneration potential. In summary, Vloom-Focus prove itself as natural neuroprotective and prebitoic agent, due to its mechanism of action, discussed below, on the nervous system, gut-brain axis and its rich bio-compounds, H.erinaceus biomass portfolio. 

Mechanisms of action reviewed, include Vloom Focus’s naturally present neuroprotective compounds, hericenones and erinacines, which are believed to operate by crossing the blood-brain barrier (due to their small size, natural molecular composition), and to directly support the nerve and brain function there. These compounds enhance the production of Nerve Growth Factor (NGF), a neurotrophic protein crucial for brain cell survival, repair, and renewal. In addition, Vloom Focus has shown in research to stimulate the endogenous anti-inflammatory agent Lipoxin A4 production in the body and brain, elevating its observed levels. This is as well referred to as a potential mechanism behind Vloom Focus’s neuroprotective effect. Numerous studies were therefore reported on its positive outcomes in Mild Cognitive Impairment (MCI) patients, its ability to slow down the pathogenesis, in Alzheimer and Parkinson’s, and to better the symptoms of such neurodegenerative diseases, as well as sleep and mood disorders.

Vloom-Focus’s unique enzymatic activity (refer to the antioxidant table below), due to its patented production method, harvests potent antioxidant and detoxifying enzymes. This, too, is considered as a mode of action in neurological studies, for its anti-age positive outcomes. Vloom Focus’s enzymatic biomass, is pointed out as a successful tool against accumulating oxidative stress, and a relief of inflammatory build-up and damage in the body and brain. Ergo, Its unique bio-composition can contribute to the prevention and decrease of premature aging, and neural damage, due to free radicals in the environment, oxidative stress build up, and daily stress induced alterations. In addition, its gut balancing, prebiotic activity in the microbiome - suppressing the production of harmful bacteria and increasing the amount and diversity of beneficial gut bacteria - is partly considered due to the many immunomodulatory beta glucans in the Hericium erinaceus mushroom. These microbiome outcomes (re-balancing of dysbiosis), have been strongly correlated in literature with such beneficial effects on the skin, brain, mood, and overall health, as well.

In conclusion, this complex, symbiotic, evidence-based support provided to the body and brain through the intake of Vloom-Focus, is usually followed in trials for a minimum of 3 months, everyday use and so allowance of build up in the organism, and a natural, wholistic approach to disbalances within. Vloom-Focus is shown in research to help prevent and/or significantly lower age-related inflammation and cognitive decline symptoms associated with aging and diseases like MCI, Depression and Anxiety, Alzheimer's, and Parkinson's.

 

Cognition (Focus)-Memory-Stress

• Improves cognitive function, memory, and focus.
• Shown to contribute to the prevention of cognitive decline and neural loss associated with aging and diseases like Mild Cognitive Decline, Alzheimer's and Parkinson's. This is partly due to its ability to increase Nerve Growth Factor (NGF) and its antioxidant properties.
• Reduces stress and anxiety. Lion's Mane mushroom has demonstrated anxiolytic and stress-reducing properties, which may be beneficial for people who experience chronic stress or anxiety.

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Depression

• Increases mood-regulating neurotransmitters - serotonin, dopamine, norepinephrine. Associated with the re-balancing of the gut microflora.
• Promotes nerve growth, and survival, prevents further damage (BDNF and NGF).
• Reduces oxidative stress and inflammation (unique to Vloom Focus biomass’ enzymatic profile and Lipoxin A4 stimulation).
• Improves and balances gut health and microbiota (all factors linked to depression).

Mood and Sleep Disorders

• Lions mane is seen to increases BDNF levels, neurotrophic factor in addition to NGF, important for mood and sleep regulation.
• Notably improves gut health, brain-gut axis symbiotic beneficial mode of action (related to mood and sleep).
• Potentially increases mood-regulating neurotransmitters.
• Proven to reduce oxidative stress and inflamation.
  
  

Potent Antioxidant and Anti-Age 

Vloom Focus contributes to anti-aging and skin benefits as well, due to its potent Lion's Mane biomass mushroom formula (unique enzymes preserved from its patented cultivation process, illustrated in the table below).

• Maintains antioxidant and detoxifying properties throughout the body.
• Reduces oxidative stress and related stress inflammation, key factors in premature aging.
• Detoxifies and protects the body from free radical damage, due to its strong enzymatically-rich biomass.
• H. erinaceus is seen in research to elevate collagen production, an essential protein for skin elasticity and firmness. 
• Elevates Lipoxin A4 levels, an anti-inflammatory compound that can prevent the skin from further sun damage, aging, and acne.

*Cornelius C. e tal “ Comparative Enzyme Analysis of Polyporus umbellatus, Agaricus blazei, Pleurotus osteratus and Hericium erinaceus” pp 5, Clinical Journal of Mycology, 7;2009 Vol II.

 

Prebiotic and Rich Functional Food

Acts as a prebiotic agent and promotes naturally the re-balance of the gut microbiome. These changes may be linked to better blood chemistry and overall health.

• Shown to increase gut microbiota diversity.
• Promotes beneficial bacteria growth.
• Reduces harmful bacteria in the gut. 

=> Acts as a prebiotic agent and promotes naturally the re-balance of the gut microbiome. These changes may be linked to better blood chemistry and overall health. 

 

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Research & Bibliography

1. An Overview on Mushroom Polysaccharides: Health-promoting Properties, Prebiotic and Gut Microbiota Modulation Effects and Structure-function Correlation, Carbohydrate Polymers,Volume 333,2024, 1st June 2024 121978,ISSN 0144-8617 https://doi.org/10.1016/j.carbpol.2024.121978 https://www.mycologyresearch.com/articles/view/145
2. Key Mechanisms and Potential Implications of Hericium erinaceus in NLRP3 Inflammasome Activation by Reactive Oxygen Species during Alzheimer’s Disease https://www.mycologyresearch.com/articles/view/143
3. Role of NLRP3 Inflammasome Activation in Alzheimer’s Disease and Impact of Hericium erinaceus Biomass Supplementation. 
4. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8889079/
5. Hericium Erinaceus Prevents DEHP-Induced Mitochondrial Dysfunction and Apoptosis in PC12 Cells. https://pubmed.ncbi.nlm.nih.gov/32244920/ 
6. Antioxidants, Hormetic Nutrition, and Autism. Curr Neuropharmacol. https://www.mdpi.com/1422-0067/23/6/3033
7. Redox modulation of cellular stress response and lipoxin A4 expression by Hericium Erinaceus in rat brain: relevance to Alzheimer’s disease pathogenesis https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938991
8. Hericium erinaceus and Coriolus versicolor Modulate Molecular and Biochemical Changes after Traumatic Brain Injury. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8228340/
9. Natural Compounds such as Hericium erinaceus and Coriolus versicolor Modulate Neuroinflammation, Oxidative Stress and Lipoxin A4 Expression in Rotenone-Induced Parkinson’s Disease in Mice. https://pubmed.ncbi.nlm.nih.gov/36289766/
10. Central Nervous System Profiling of Hericium erinaceus Biomass Powder by an Electropharmacogram Using Spectral Field Power in Conscious Freely Moving Rats. https://www.aneid.pt/aneidpress/journals/cjm-vol6-1-2010557/
11. Improving Effects of the Mushroom Yamabushitake (Hericium erinaceus) on Mild Cognitive Impairment: A Double-blind Placebo-controlled Clinical Trial. https://pubmed.ncbi.nlm.nih.gov/18844328/